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Regulation of Bottromycin Biosynthesis Involves an Internal Transcriptional Start Site and a Cluster-Situated Modulator

Bottromycin is a ribosomally synthesized and post-translationally modified peptide (RiPP) produced by several streptomycetes, including the plant pathogen Streptomyces scabies. There is significant interest in this molecule as it possesses strong antibacterial activity against clinically relevant mu...

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Detalles Bibliográficos
Autores principales: Vior, Natalia M., Cea-Torrescassana, Eva, Eyles, Tom H., Chandra, Govind, Truman, Andrew W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113386/
https://www.ncbi.nlm.nih.gov/pubmed/32273872
http://dx.doi.org/10.3389/fmicb.2020.00495