Aerobic synthesis of N-sulfonylamidines mediated by N-heterocyclic carbene copper(I) catalysts

A new catalytic strategy for the one-pot synthesis of N-sulfonylamidines is described. The cationic copper(I) complexes were found to be highly active and efficient under mild conditions in air and in the absence of solvent. A copper acetylide is proposed as key intermediate in this transformation.

Detalles Bibliográficos
Autores principales: Lazreg, Faïma, Vasseur, Marie, Slawin, Alexandra M Z, Cazin, Catherine S J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2020
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113546/
https://www.ncbi.nlm.nih.gov/pubmed/32273908
http://dx.doi.org/10.3762/bjoc.16.43
_version_ 1783513696442515456
author Lazreg, Faïma
Vasseur, Marie
Slawin, Alexandra M Z
Cazin, Catherine S J
author_facet Lazreg, Faïma
Vasseur, Marie
Slawin, Alexandra M Z
Cazin, Catherine S J
author_sort Lazreg, Faïma
collection PubMed
description A new catalytic strategy for the one-pot synthesis of N-sulfonylamidines is described. The cationic copper(I) complexes were found to be highly active and efficient under mild conditions in air and in the absence of solvent. A copper acetylide is proposed as key intermediate in this transformation.
format Online
Article
Text
id pubmed-7113546
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Beilstein-Institut
record_format MEDLINE/PubMed
spelling pubmed-71135462020-04-09 Aerobic synthesis of N-sulfonylamidines mediated by N-heterocyclic carbene copper(I) catalysts Lazreg, Faïma Vasseur, Marie Slawin, Alexandra M Z Cazin, Catherine S J Beilstein J Org Chem Full Research Paper A new catalytic strategy for the one-pot synthesis of N-sulfonylamidines is described. The cationic copper(I) complexes were found to be highly active and efficient under mild conditions in air and in the absence of solvent. A copper acetylide is proposed as key intermediate in this transformation. Beilstein-Institut 2020-03-24 /pmc/articles/PMC7113546/ /pubmed/32273908 http://dx.doi.org/10.3762/bjoc.16.43 Text en Copyright © 2020, Lazreg et al. https://creativecommons.org/licenses/by/4.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0). Please note that the reuse, redistribution and reproduction in particular requires that the authors and source are credited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Full Research Paper
Lazreg, Faïma
Vasseur, Marie
Slawin, Alexandra M Z
Cazin, Catherine S J
Aerobic synthesis of N-sulfonylamidines mediated by N-heterocyclic carbene copper(I) catalysts
title Aerobic synthesis of N-sulfonylamidines mediated by N-heterocyclic carbene copper(I) catalysts
title_full Aerobic synthesis of N-sulfonylamidines mediated by N-heterocyclic carbene copper(I) catalysts
title_fullStr Aerobic synthesis of N-sulfonylamidines mediated by N-heterocyclic carbene copper(I) catalysts
title_full_unstemmed Aerobic synthesis of N-sulfonylamidines mediated by N-heterocyclic carbene copper(I) catalysts
title_short Aerobic synthesis of N-sulfonylamidines mediated by N-heterocyclic carbene copper(I) catalysts
title_sort aerobic synthesis of n-sulfonylamidines mediated by n-heterocyclic carbene copper(i) catalysts
topic Full Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113546/
https://www.ncbi.nlm.nih.gov/pubmed/32273908
http://dx.doi.org/10.3762/bjoc.16.43
work_keys_str_mv AT lazregfaima aerobicsynthesisofnsulfonylamidinesmediatedbynheterocycliccarbenecoppericatalysts
AT vasseurmarie aerobicsynthesisofnsulfonylamidinesmediatedbynheterocycliccarbenecoppericatalysts
AT slawinalexandramz aerobicsynthesisofnsulfonylamidinesmediatedbynheterocycliccarbenecoppericatalysts
AT cazincatherinesj aerobicsynthesisofnsulfonylamidinesmediatedbynheterocycliccarbenecoppericatalysts

Ejemplares similares