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Peptide Self-Assembly Is Linked to Antibacterial, but Not Antifungal, Activity of Histatin 5 Derivatives

The rise of multidrug-resistant pathogens has awakened interest in new drug candidates such as antimicrobial peptides and their derivatives. Recent work suggests that some antimicrobial peptides have the ability to self-assemble into ordered amyloid-like nanostructures which facilitate their antibac...

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Detalles Bibliográficos
Autores principales: Schnaider, Lee, Rosenberg, Alexander, Kreiser, Topaz, Kolusheva, Sofiya, Gazit, Ehud, Berman, Judith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113582/
https://www.ncbi.nlm.nih.gov/pubmed/32238567
http://dx.doi.org/10.1128/mSphere.00021-20