Identification and evaluation of potent Middle East respiratory syndrome coronavirus (MERS-CoV) 3CL(Pro) inhibitors

Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe acute respiratory illness with fever, cough and shortness of breath. Up to date, it has resulted in 1826 human infections, including 649 deaths. Analogous to picornavirus 3C protease (3C(pro)), 3C-like protease (3CL(pro)) is criti...

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Detalles Bibliográficos
Autores principales: Kumar, Vathan, Shin, Jin Soo, Shie, Jiun-Jie, Ku, Keun Bon, Kim, Chonsaeng, Go, Yun Young, Huang, Kai-Fa, Kim, Meehyein, Liang, Po-Huang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113684/
https://www.ncbi.nlm.nih.gov/pubmed/28216367
http://dx.doi.org/10.1016/j.antiviral.2017.02.007

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