Prophylactic and therapeutic efficacy of mAb treatment against MERS-CoV in common marmosets

The high case-fatality rate of confirmed MERS-CoV infections underlines the urgent need for an effective treatment to reduce the disease severity and mortality. REGN3051 and REGN3048 are two fully human neutralizing monoclonal antibodies (mAb) against MERS-CoV that reduced virus replication in mice...

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Detalles Bibliográficos
Autores principales: de Wit, Emmie, Feldmann, Friederike, Okumura, Atsushi, Horne, Eva, Haddock, Elaine, Saturday, Greg, Scott, Dana, Erlandson, Karl J., Stahl, Neil, Lipsich, Leah, Kyratsous, Christos A., Feldmann, Heinz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113689/
https://www.ncbi.nlm.nih.gov/pubmed/29885377
http://dx.doi.org/10.1016/j.antiviral.2018.06.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113689/
https://www.ncbi.nlm.nih.gov/pubmed/29885377
http://dx.doi.org/10.1016/j.antiviral.2018.06.006

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