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Prophylactic and therapeutic efficacy of mAb treatment against MERS-CoV in common marmosets
The high case-fatality rate of confirmed MERS-CoV infections underlines the urgent need for an effective treatment to reduce the disease severity and mortality. REGN3051 and REGN3048 are two fully human neutralizing monoclonal antibodies (mAb) against MERS-CoV that reduced virus replication in mice...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier B.V.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113689/ https://www.ncbi.nlm.nih.gov/pubmed/29885377 http://dx.doi.org/10.1016/j.antiviral.2018.06.006 |