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Malignant peripheral nerve sheath tumor in the nasopharynx and oropharynx: a case report

Malignant peripheral nerve sheath tumor (MPNST) in the nasopharynx and oropharynx has not been reported. A 3-year-old boy was referred to hospital after experiencing intermittent inspiratory dyspnea for 3 years. Preoperative imaging showed that the lymph nodes were clear. Therefore, neck lymph node...

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Autores principales: Gu, Wen-Jing, Chang, Peng-yu, Wang, Ling-Jing, Zhu, Wei, Zhou, Hong-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113698/
https://www.ncbi.nlm.nih.gov/pubmed/31937162
http://dx.doi.org/10.1177/0300060519897184
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author Gu, Wen-Jing
Chang, Peng-yu
Wang, Ling-Jing
Zhu, Wei
Zhou, Hong-Wei
author_facet Gu, Wen-Jing
Chang, Peng-yu
Wang, Ling-Jing
Zhu, Wei
Zhou, Hong-Wei
author_sort Gu, Wen-Jing
collection PubMed
description Malignant peripheral nerve sheath tumor (MPNST) in the nasopharynx and oropharynx has not been reported. A 3-year-old boy was referred to hospital after experiencing intermittent inspiratory dyspnea for 3 years. Preoperative imaging showed that the lymph nodes were clear. Therefore, neck lymph node dissection was not performed during the operation. This could have reduced the collateral damage. Complete excision and radiotherapy were performed because of the pathological diagnosis of MPNST. Because of the high location of the tumor, we chose the transoral approach instead of the cervical approach, avoiding tracheotomy, and we effectively improved the quality of life of the child. A mass in the nasopharynx and oropharynx was diagnosed pathologically as an MPNST after surgery. The patient’s inspiratory dyspnea was resolved. No recurrence was observed during a 3-year follow-up. After review of our case, we found that postoperative recovery in our patient was closely related to accurate preoperative imaging assessment, the choice of operation methods, thorough resection, and postoperative neoadjuvant radiotherapy. Prevertebral fascia acted as a barrier to surround the mass and prevented it from growing further toward the vertebral body, which was important for a good prognosis. Children undergoing tracheotomy often have long tube management and difficult extubation.
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spelling pubmed-71136982020-04-09 Malignant peripheral nerve sheath tumor in the nasopharynx and oropharynx: a case report Gu, Wen-Jing Chang, Peng-yu Wang, Ling-Jing Zhu, Wei Zhou, Hong-Wei J Int Med Res Case Report Malignant peripheral nerve sheath tumor (MPNST) in the nasopharynx and oropharynx has not been reported. A 3-year-old boy was referred to hospital after experiencing intermittent inspiratory dyspnea for 3 years. Preoperative imaging showed that the lymph nodes were clear. Therefore, neck lymph node dissection was not performed during the operation. This could have reduced the collateral damage. Complete excision and radiotherapy were performed because of the pathological diagnosis of MPNST. Because of the high location of the tumor, we chose the transoral approach instead of the cervical approach, avoiding tracheotomy, and we effectively improved the quality of life of the child. A mass in the nasopharynx and oropharynx was diagnosed pathologically as an MPNST after surgery. The patient’s inspiratory dyspnea was resolved. No recurrence was observed during a 3-year follow-up. After review of our case, we found that postoperative recovery in our patient was closely related to accurate preoperative imaging assessment, the choice of operation methods, thorough resection, and postoperative neoadjuvant radiotherapy. Prevertebral fascia acted as a barrier to surround the mass and prevented it from growing further toward the vertebral body, which was important for a good prognosis. Children undergoing tracheotomy often have long tube management and difficult extubation. SAGE Publications 2020-01-15 /pmc/articles/PMC7113698/ /pubmed/31937162 http://dx.doi.org/10.1177/0300060519897184 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by-nc/4.0/ Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Gu, Wen-Jing
Chang, Peng-yu
Wang, Ling-Jing
Zhu, Wei
Zhou, Hong-Wei
Malignant peripheral nerve sheath tumor in the nasopharynx and oropharynx: a case report
title Malignant peripheral nerve sheath tumor in the nasopharynx and oropharynx: a case report
title_full Malignant peripheral nerve sheath tumor in the nasopharynx and oropharynx: a case report
title_fullStr Malignant peripheral nerve sheath tumor in the nasopharynx and oropharynx: a case report
title_full_unstemmed Malignant peripheral nerve sheath tumor in the nasopharynx and oropharynx: a case report
title_short Malignant peripheral nerve sheath tumor in the nasopharynx and oropharynx: a case report
title_sort malignant peripheral nerve sheath tumor in the nasopharynx and oropharynx: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113698/
https://www.ncbi.nlm.nih.gov/pubmed/31937162
http://dx.doi.org/10.1177/0300060519897184
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