Cargando…

Intraoperative ultrasound-guided lumpectomy versus wire-guided excision for nonpalpable breast cancer

OBJECTIVE: This study was designed to compare the margin clearance and re-excision rates of ultrasound (US)- and wire-guided excision in a large number of patients with nonpalpable breast cancer. METHODS: In total, 520 women who were histologically diagnosed with nonpalpable breast cancer were recru...

Descripción completa

Detalles Bibliográficos
Autores principales: Hu, Xin, Li, Si, Jiang, Yi, Wei, Wei, Ji, Yinan, Li, Qiuyun, Jiang, Zongbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113704/
https://www.ncbi.nlm.nih.gov/pubmed/31937169
http://dx.doi.org/10.1177/0300060519896707
_version_ 1783513729599537152
author Hu, Xin
Li, Si
Jiang, Yi
Wei, Wei
Ji, Yinan
Li, Qiuyun
Jiang, Zongbin
author_facet Hu, Xin
Li, Si
Jiang, Yi
Wei, Wei
Ji, Yinan
Li, Qiuyun
Jiang, Zongbin
author_sort Hu, Xin
collection PubMed
description OBJECTIVE: This study was designed to compare the margin clearance and re-excision rates of ultrasound (US)- and wire-guided excision in a large number of patients with nonpalpable breast cancer. METHODS: In total, 520 women who were histologically diagnosed with nonpalpable breast cancer were recruited in this study. All nonpalpable lesions were visible by US. The patients were randomly divided into two groups: those who underwent wire-guided breast-conserving surgery (BCS) and those who underwent US-guided BCS. Re-excision rates and positive surgical margins were recorded. RESULTS: A total of 262 patients underwent US-guided excision and 258 patients underwent wire-guided excision. No differences were found in tumor or patient characteristics. The positive margin rate was 4.6% in the US-guided group and 19.4% in the wire-guided group with a significant difference. Age, menopausal status, excision volume, histological grade, and tumor type significantly influenced the positive surgical margin rate. The intraoperative re-excision rate was significantly lower in the US-guided group than wire-guided group (11.1% vs. 24.0%, respectively). CONCLUSIONS: US-guided BCS seems to be more effective than wire-guided BCS for treatment of nonpalpable breast cancers in terms of the margin clearance and re-excision rates. Patients can avoid the discomfort caused by preoperative wire placement.
format Online
Article
Text
id pubmed-7113704
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher SAGE Publications
record_format MEDLINE/PubMed
spelling pubmed-71137042020-04-09 Intraoperative ultrasound-guided lumpectomy versus wire-guided excision for nonpalpable breast cancer Hu, Xin Li, Si Jiang, Yi Wei, Wei Ji, Yinan Li, Qiuyun Jiang, Zongbin J Int Med Res Prospective Clinical Research Report OBJECTIVE: This study was designed to compare the margin clearance and re-excision rates of ultrasound (US)- and wire-guided excision in a large number of patients with nonpalpable breast cancer. METHODS: In total, 520 women who were histologically diagnosed with nonpalpable breast cancer were recruited in this study. All nonpalpable lesions were visible by US. The patients were randomly divided into two groups: those who underwent wire-guided breast-conserving surgery (BCS) and those who underwent US-guided BCS. Re-excision rates and positive surgical margins were recorded. RESULTS: A total of 262 patients underwent US-guided excision and 258 patients underwent wire-guided excision. No differences were found in tumor or patient characteristics. The positive margin rate was 4.6% in the US-guided group and 19.4% in the wire-guided group with a significant difference. Age, menopausal status, excision volume, histological grade, and tumor type significantly influenced the positive surgical margin rate. The intraoperative re-excision rate was significantly lower in the US-guided group than wire-guided group (11.1% vs. 24.0%, respectively). CONCLUSIONS: US-guided BCS seems to be more effective than wire-guided BCS for treatment of nonpalpable breast cancers in terms of the margin clearance and re-excision rates. Patients can avoid the discomfort caused by preoperative wire placement. SAGE Publications 2020-01-15 /pmc/articles/PMC7113704/ /pubmed/31937169 http://dx.doi.org/10.1177/0300060519896707 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by-nc/4.0/ Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Prospective Clinical Research Report
Hu, Xin
Li, Si
Jiang, Yi
Wei, Wei
Ji, Yinan
Li, Qiuyun
Jiang, Zongbin
Intraoperative ultrasound-guided lumpectomy versus wire-guided excision for nonpalpable breast cancer
title Intraoperative ultrasound-guided lumpectomy versus wire-guided excision for nonpalpable breast cancer
title_full Intraoperative ultrasound-guided lumpectomy versus wire-guided excision for nonpalpable breast cancer
title_fullStr Intraoperative ultrasound-guided lumpectomy versus wire-guided excision for nonpalpable breast cancer
title_full_unstemmed Intraoperative ultrasound-guided lumpectomy versus wire-guided excision for nonpalpable breast cancer
title_short Intraoperative ultrasound-guided lumpectomy versus wire-guided excision for nonpalpable breast cancer
title_sort intraoperative ultrasound-guided lumpectomy versus wire-guided excision for nonpalpable breast cancer
topic Prospective Clinical Research Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113704/
https://www.ncbi.nlm.nih.gov/pubmed/31937169
http://dx.doi.org/10.1177/0300060519896707
work_keys_str_mv AT huxin intraoperativeultrasoundguidedlumpectomyversuswireguidedexcisionfornonpalpablebreastcancer
AT lisi intraoperativeultrasoundguidedlumpectomyversuswireguidedexcisionfornonpalpablebreastcancer
AT jiangyi intraoperativeultrasoundguidedlumpectomyversuswireguidedexcisionfornonpalpablebreastcancer
AT weiwei intraoperativeultrasoundguidedlumpectomyversuswireguidedexcisionfornonpalpablebreastcancer
AT jiyinan intraoperativeultrasoundguidedlumpectomyversuswireguidedexcisionfornonpalpablebreastcancer
AT liqiuyun intraoperativeultrasoundguidedlumpectomyversuswireguidedexcisionfornonpalpablebreastcancer
AT jiangzongbin intraoperativeultrasoundguidedlumpectomyversuswireguidedexcisionfornonpalpablebreastcancer