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Tectonic keratoplasty using small incision lenticule extraction-extracted intrastromal lenticule for corneal lesions

OBJECTIVE: This study investigated an alternative approach for obtaining donor corneas for keratoplasty that can be used in nations with high corneal demand and high costs for treatment of non-healing ulcers or lesions. METHODS: Eighteen patients (18 eyes) who underwent tectonic keratoplasty using s...

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Autores principales: Pant, Om Prakash, Hao, Ji-long, Zhou, Dan-dan, Pant, Manju, Lu, Cheng-wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113716/
https://www.ncbi.nlm.nih.gov/pubmed/31975635
http://dx.doi.org/10.1177/0300060519897668
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author Pant, Om Prakash
Hao, Ji-long
Zhou, Dan-dan
Pant, Manju
Lu, Cheng-wei
author_facet Pant, Om Prakash
Hao, Ji-long
Zhou, Dan-dan
Pant, Manju
Lu, Cheng-wei
author_sort Pant, Om Prakash
collection PubMed
description OBJECTIVE: This study investigated an alternative approach for obtaining donor corneas for keratoplasty that can be used in nations with high corneal demand and high costs for treatment of non-healing ulcers or lesions. METHODS: Eighteen patients (18 eyes) who underwent tectonic keratoplasty using small incision refractive lenticule extraction (SMILE)-extracted lenticule were included. Data were recorded regarding age, corneal status, corneal lesion location and size, preoperative and postoperative visual acuity, lenticule layer, and additional medical history. RESULTS: Corneal thinning and corneal perforation in 13 and 5 patients, respectively, were treated with tectonic keratoplasty using SMILE-extracted lenticule. After tectonic keratoplasty, globe integrity was maintained in 16 of the 18 patients. The mean decimal visual acuity improved from 0.2555±0.3326 preoperatively to 0.3303±0.3487 at the final follow-up. Visual acuity improvement was greater in patients with corneal perforation than in patients with corneal thinning. In addition, visual acuity was most improved in patients with infratemporal lesions. CONCLUSION: Tectonic keratoplasty using SMILE-extracted lenticule is a comparatively safe, effective, and reliable alternative approach for the treatment of corneal lesions.
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spelling pubmed-71137162020-04-09 Tectonic keratoplasty using small incision lenticule extraction-extracted intrastromal lenticule for corneal lesions Pant, Om Prakash Hao, Ji-long Zhou, Dan-dan Pant, Manju Lu, Cheng-wei J Int Med Res Retrospective Clinical Research Report OBJECTIVE: This study investigated an alternative approach for obtaining donor corneas for keratoplasty that can be used in nations with high corneal demand and high costs for treatment of non-healing ulcers or lesions. METHODS: Eighteen patients (18 eyes) who underwent tectonic keratoplasty using small incision refractive lenticule extraction (SMILE)-extracted lenticule were included. Data were recorded regarding age, corneal status, corneal lesion location and size, preoperative and postoperative visual acuity, lenticule layer, and additional medical history. RESULTS: Corneal thinning and corneal perforation in 13 and 5 patients, respectively, were treated with tectonic keratoplasty using SMILE-extracted lenticule. After tectonic keratoplasty, globe integrity was maintained in 16 of the 18 patients. The mean decimal visual acuity improved from 0.2555±0.3326 preoperatively to 0.3303±0.3487 at the final follow-up. Visual acuity improvement was greater in patients with corneal perforation than in patients with corneal thinning. In addition, visual acuity was most improved in patients with infratemporal lesions. CONCLUSION: Tectonic keratoplasty using SMILE-extracted lenticule is a comparatively safe, effective, and reliable alternative approach for the treatment of corneal lesions. SAGE Publications 2020-01-24 /pmc/articles/PMC7113716/ /pubmed/31975635 http://dx.doi.org/10.1177/0300060519897668 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by-nc/4.0/ Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Retrospective Clinical Research Report
Pant, Om Prakash
Hao, Ji-long
Zhou, Dan-dan
Pant, Manju
Lu, Cheng-wei
Tectonic keratoplasty using small incision lenticule extraction-extracted intrastromal lenticule for corneal lesions
title Tectonic keratoplasty using small incision lenticule extraction-extracted intrastromal lenticule for corneal lesions
title_full Tectonic keratoplasty using small incision lenticule extraction-extracted intrastromal lenticule for corneal lesions
title_fullStr Tectonic keratoplasty using small incision lenticule extraction-extracted intrastromal lenticule for corneal lesions
title_full_unstemmed Tectonic keratoplasty using small incision lenticule extraction-extracted intrastromal lenticule for corneal lesions
title_short Tectonic keratoplasty using small incision lenticule extraction-extracted intrastromal lenticule for corneal lesions
title_sort tectonic keratoplasty using small incision lenticule extraction-extracted intrastromal lenticule for corneal lesions
topic Retrospective Clinical Research Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113716/
https://www.ncbi.nlm.nih.gov/pubmed/31975635
http://dx.doi.org/10.1177/0300060519897668
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