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Tectonic keratoplasty using small incision lenticule extraction-extracted intrastromal lenticule for corneal lesions
OBJECTIVE: This study investigated an alternative approach for obtaining donor corneas for keratoplasty that can be used in nations with high corneal demand and high costs for treatment of non-healing ulcers or lesions. METHODS: Eighteen patients (18 eyes) who underwent tectonic keratoplasty using s...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113716/ https://www.ncbi.nlm.nih.gov/pubmed/31975635 http://dx.doi.org/10.1177/0300060519897668 |
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author | Pant, Om Prakash Hao, Ji-long Zhou, Dan-dan Pant, Manju Lu, Cheng-wei |
author_facet | Pant, Om Prakash Hao, Ji-long Zhou, Dan-dan Pant, Manju Lu, Cheng-wei |
author_sort | Pant, Om Prakash |
collection | PubMed |
description | OBJECTIVE: This study investigated an alternative approach for obtaining donor corneas for keratoplasty that can be used in nations with high corneal demand and high costs for treatment of non-healing ulcers or lesions. METHODS: Eighteen patients (18 eyes) who underwent tectonic keratoplasty using small incision refractive lenticule extraction (SMILE)-extracted lenticule were included. Data were recorded regarding age, corneal status, corneal lesion location and size, preoperative and postoperative visual acuity, lenticule layer, and additional medical history. RESULTS: Corneal thinning and corneal perforation in 13 and 5 patients, respectively, were treated with tectonic keratoplasty using SMILE-extracted lenticule. After tectonic keratoplasty, globe integrity was maintained in 16 of the 18 patients. The mean decimal visual acuity improved from 0.2555±0.3326 preoperatively to 0.3303±0.3487 at the final follow-up. Visual acuity improvement was greater in patients with corneal perforation than in patients with corneal thinning. In addition, visual acuity was most improved in patients with infratemporal lesions. CONCLUSION: Tectonic keratoplasty using SMILE-extracted lenticule is a comparatively safe, effective, and reliable alternative approach for the treatment of corneal lesions. |
format | Online Article Text |
id | pubmed-7113716 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-71137162020-04-09 Tectonic keratoplasty using small incision lenticule extraction-extracted intrastromal lenticule for corneal lesions Pant, Om Prakash Hao, Ji-long Zhou, Dan-dan Pant, Manju Lu, Cheng-wei J Int Med Res Retrospective Clinical Research Report OBJECTIVE: This study investigated an alternative approach for obtaining donor corneas for keratoplasty that can be used in nations with high corneal demand and high costs for treatment of non-healing ulcers or lesions. METHODS: Eighteen patients (18 eyes) who underwent tectonic keratoplasty using small incision refractive lenticule extraction (SMILE)-extracted lenticule were included. Data were recorded regarding age, corneal status, corneal lesion location and size, preoperative and postoperative visual acuity, lenticule layer, and additional medical history. RESULTS: Corneal thinning and corneal perforation in 13 and 5 patients, respectively, were treated with tectonic keratoplasty using SMILE-extracted lenticule. After tectonic keratoplasty, globe integrity was maintained in 16 of the 18 patients. The mean decimal visual acuity improved from 0.2555±0.3326 preoperatively to 0.3303±0.3487 at the final follow-up. Visual acuity improvement was greater in patients with corneal perforation than in patients with corneal thinning. In addition, visual acuity was most improved in patients with infratemporal lesions. CONCLUSION: Tectonic keratoplasty using SMILE-extracted lenticule is a comparatively safe, effective, and reliable alternative approach for the treatment of corneal lesions. SAGE Publications 2020-01-24 /pmc/articles/PMC7113716/ /pubmed/31975635 http://dx.doi.org/10.1177/0300060519897668 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by-nc/4.0/ Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Retrospective Clinical Research Report Pant, Om Prakash Hao, Ji-long Zhou, Dan-dan Pant, Manju Lu, Cheng-wei Tectonic keratoplasty using small incision lenticule extraction-extracted intrastromal lenticule for corneal lesions |
title | Tectonic keratoplasty using small incision lenticule extraction-extracted intrastromal lenticule for corneal lesions |
title_full | Tectonic keratoplasty using small incision lenticule extraction-extracted intrastromal lenticule for corneal lesions |
title_fullStr | Tectonic keratoplasty using small incision lenticule extraction-extracted intrastromal lenticule for corneal lesions |
title_full_unstemmed | Tectonic keratoplasty using small incision lenticule extraction-extracted intrastromal lenticule for corneal lesions |
title_short | Tectonic keratoplasty using small incision lenticule extraction-extracted intrastromal lenticule for corneal lesions |
title_sort | tectonic keratoplasty using small incision lenticule extraction-extracted intrastromal lenticule for corneal lesions |
topic | Retrospective Clinical Research Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113716/ https://www.ncbi.nlm.nih.gov/pubmed/31975635 http://dx.doi.org/10.1177/0300060519897668 |
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