Cargando…
The molecular tweezer CLR01 inhibits Ebola and Zika virus infection
Ebola (EBOV) and Zika viruses (ZIKV) are responsible for recent global health threats. As no preventive vaccines or antiviral drugs against these two re-emerging pathogens are available, we evaluated whether the molecular tweezer CLR01 may inhibit EBOV and ZIKV infection. This small molecule has pre...
Autores principales: | Röcker, Annika E., Müller, Janis A., Dietzel, Erik, Harms, Mirja, Krüger, Franziska, Heid, Christian, Sowislok, Andrea, Riber, Camilla Frich, Kupke, Alexandra, Lippold, Sina, von Einem, Jens, Beer, Judith, Knöll, Bernd, Becker, Stephan, Schmidt-Chanasit, Jonas, Otto, Markus, Vapalahti, Olli, Zelikin, Alexander N., Bitan, Gal, Schrader, Thomas, Münch, Jan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113745/ https://www.ncbi.nlm.nih.gov/pubmed/29428508 http://dx.doi.org/10.1016/j.antiviral.2018.02.003 |
Ejemplares similares
-
Amyloid β-Protein Assembly: The Effect
of Molecular Tweezers CLR01 and CLR03
por: Zheng, Xueyun, et al.
Publicado: (2015) -
The
Molecular Tweezer CLR01 Stabilizes a Disordered
Protein–Protein Interface
por: Bier, David, et al.
Publicado: (2017) -
The Molecular Tweezer CLR01 Inhibits Antibody-Resistant Cell-to-Cell Spread of Human Cytomegalovirus
por: Brenner, Sina, et al.
Publicado: (2021) -
Supramolecular
Mechanism of Viral Envelope Disruption
by Molecular Tweezers
por: Weil, Tatjana, et al.
Publicado: (2020) -
Safety and pharmacological characterization of the molecular tweezer CLR01 – a broad-spectrum inhibitor of amyloid proteins’ toxicity
por: Attar, Aida, et al.
Publicado: (2014)