Cargando…

MERS-CoV spike protein: Targets for vaccines and therapeutics

The disease outbreak caused by Middle East respiratory syndrome coronavirus (MERS-CoV) is still ongoing in the Middle East. Over 1700 people have been infected since it was first reported in September 2012. Despite great efforts, licensed vaccines or therapeutics against MERS-CoV remain unavailable....

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Qihui, Wong, Gary, Lu, Guangwen, Yan, Jinghua, Gao, George F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier B.V. 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113765/ https://www.ncbi.nlm.nih.gov/pubmed/27468951 http://dx.doi.org/10.1016/j.antiviral.2016.07.015

Ejemplares similares

Bat-to-human: spike features determining ‘host jump’ of coronaviruses SARS-CoV, MERS-CoV, and beyond
por: Lu, Guangwen, et al.
Publicado: (2015)

A humanized neutralizing antibody against MERS-CoV targeting the receptor-binding domain of the spike protein
por: Li, Yan, et al.
Publicado: (2015)

Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains
por: Yuan, Yuan, et al.
Publicado: (2017)

Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26
por: Lu, Guangwen, et al.
Publicado: (2013)

MERS-CoV spike nanoparticles protect mice from MERS-CoV infection
por: Coleman, Christopher M., et al.
Publicado: (2017)

T-cell immunity of SARS-CoV: Implications for vaccine development against MERS-CoV
por: Liu, William J., et al.
Publicado: (2017)

Immunogenicity of Candidate MERS-CoV DNA Vaccines Based on the Spike Protein
por: Al-amri, Sawsan S., et al.
Publicado: (2017)

The recombinant N-terminal domain of spike proteins is a potential vaccine against Middle East respiratory syndrome coronavirus (MERS-CoV) infection
por: Jiaming, Lan, et al.
Publicado: (2017)

Unlocking COVID therapeutic targets: A structure-based rationale against SARS-CoV-2, SARS-CoV and MERS-CoV Spike
por: Trigueiro-Louro, João, et al.
Publicado: (2020)

The MERS-CoV Receptor DPP4 as a Candidate Binding Target of the SARS-CoV-2 Spike
por: Li, Yu, et al.
Publicado: (2020)

The MERS-CoV Receptor DPP4 as a Candidate Binding Target of the SARS-CoV-2 Spike
por: Li, Yu, et al.
Publicado: (2020)

Bat Origins of MERS-CoV Supported by Bat Coronavirus HKU4 Usage of Human Receptor CD26
por: Wang, Qihui, et al.
Publicado: (2014)

Middle East respiratory syndrome coronavirus (MERS-CoV) entry inhibitors targeting spike protein
por: Xia, Shuai, et al.
Publicado: (2014)

A Truncated Receptor-Binding Domain of MERS-CoV Spike Protein Potently Inhibits MERS-CoV Infection and Induces Strong Neutralizing Antibody Responses: Implication for Developing Therapeutics and Vaccines
por: Du, Lanying, et al.
Publicado: (2013)

Inclusion of MERS‐spike protein ELISA in algorithm to determine serologic evidence of MERS‐CoV infection
por: Trivedi, Suvang, et al.
Publicado: (2017)

Correction: A Truncated Receptor-Binding Domain of MERS-CoV Spike Protein Potently Inhibits MERS-CoV Infection and Induces Strong Neutralizing Antibody Responses: Implication for Developing Therapeutics and Vaccines
por: Du, Lanying, et al.
Publicado: (2022)

Origins of HIV, HCoV-HKU1, SFTSV, and MERS-CoV and Beyond
por: Liu, Wenli, et al.
Publicado: (2022)

The spike protein of SARS-CoV — a target for vaccine and therapeutic development
por: Du, Lanying, et al.
Publicado: (2009)

Genetic diversity of MERS-CoV spike protein gene in Saudi Arabia
por: Sohrab, Sayed S., et al.
Publicado: (2020)

Persistence of MERS-CoV-spike-specific B cells and antibodies after late third immunization with the MVA-MERS-S vaccine
por: Weskamm, Leonie M., et al.
Publicado: (2022)

A novel neutralizing monoclonal antibody targeting the N-terminal domain of the MERS-CoV spike protein
por: Chen, Yingzhu, et al.
Publicado: (2017)

A novel neutralizing monoclonal antibody targeting the N-terminal domain of the MERS-CoV spike protein
por: Chen, Yingzhu, et al.
Publicado: (2017)

MERS-CoV and SARS-CoV-2 replication can be inhibited by targeting the interaction between the viral spike protein and the nucleocapsid protein
por: Park, Byoung Kwon, et al.
Publicado: (2021)

Cross-Protection against MERS-CoV by Prime-Boost Vaccination Using Viral Spike DNA and Protein
por: Choi, Jung-ah, et al.
Publicado: (2020)

Safe, high-throughput screening of natural compounds of MERS-CoV entry inhibitors using a pseudovirus expressing MERS-CoV spike protein
por: Kim, Ji Yeun, et al.
Publicado: (2018)

Secondary Structures of MERS-CoV, SARS-CoV, and SARS-CoV-2 Spike Proteins Revealed by Infrared Vibrational Spectroscopy
por: D’Arco, Annalisa, et al.
Publicado: (2023)

Advances in MERS-CoV Vaccines and Therapeutics Based on the Receptor-Binding Domain
por: Zhou, Yusen, et al.
Publicado: (2019)

MERS-CoV
por: Müller, Marcel A
Publicado: (2014)

An optimised method for the production of MERS-CoV spike expressing viral pseudotypes
por: Grehan, K., et al.
Publicado: (2015)

Variations in Spike Glycoprotein Gene of MERS-CoV, South Korea, 2015
por: Kim, Dae-Won, et al.
Publicado: (2016)

Structures of MERS-CoV spike glycoprotein in complex with sialoside attachment receptors
por: Park, Young-Jun, et al.
Publicado: (2019)

Inability of rat DPP4 to allow MERS-CoV infection revealed by using a VSV pseudotype bearing truncated MERS-CoV spike protein
por: Fukuma, Aiko, et al.
Publicado: (2015)

The Sialoside-Binding Pocket of SARS-CoV-2 Spike Glycoprotein Structurally Resembles MERS-CoV
por: Awasthi, Mayanka, et al.
Publicado: (2020)

Comprehensive Structural and Molecular Comparison of Spike Proteins of SARS-CoV-2, SARS-CoV and MERS-CoV, and Their Interactions with ACE2
por: Hatmal, Ma’mon M., et al.
Publicado: (2020)

Tailoring Subunit Vaccine Immunity with Adjuvant Combinations and Delivery Routes Using the Middle East Respiratory Coronavirus (MERS-CoV) Receptor-Binding Domain as an Antigen
por: Lan, Jiaming, et al.
Publicado: (2014)

Crystal structures of Middle East respiratory syndrome coronavirus (MERS-CoV) spike protein
Publicado: (2013)

Evaluation of candidate vaccine approaches for MERS-CoV
por: Wang, Lingshu, et al.
Publicado: (2015)

Vaccines for the prevention against the threat of MERS-CoV
por: Du, Lanying, et al.
Publicado: (2016)

Vaccination strategies for mitigation of MERS-CoV outbreaks
por: Bosaeed, Mohammad, et al.
Publicado: (2023)

A chimeric MERS-CoV virus-like particle vaccine protects mice against MERS-CoV challenge
por: Park, Jung-Eun, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_vrpu36up6e2slvv83bka5phs64