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Synthesis and anti-influenza virus activity of 4-oxo- or thioxo-4,5-dihydrofuro[3,4-c]pyridin-3(1H)-ones

A target-free approach was applied to discover anti-influenza viral compounds, where influenza infected Madin–Darby canine kidney cells were treated 7500 different small organic chemicals individually and reduction of virus-induced cytopathic effect was measured. One of the hit compounds was (Z)-1-(...

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Detalles Bibliográficos
Autores principales:	Jang, Ye Jin, Achary, Raghavendra, Lee, Hye Won, Lee, Hyo Jin, Lee, Chong-Kyo, Han, Soo Bong, Jung, Young-Sik, Kang, Nam Sook, Kim, Pilho, Kim, Meehyein
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier B.V. 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113773/ https://www.ncbi.nlm.nih.gov/pubmed/24794525 http://dx.doi.org/10.1016/j.antiviral.2014.04.013

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