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Association of Rare PTGIS Variants With Susceptibility and Pulmonary Vascular Response in Patients With Idiopathic Pulmonary Arterial Hypertension

IMPORTANCE: Idiopathic pulmonary arterial hypertension (IPAH) is a fatal disease with high heritability; however, the bone morphogenetic protein receptor 2 (BMPR2) gene only accounts for 17% of IPAH. The genetic basis of IPAH needs further investigation. OBJECTIVE: To identify novel IPAH susceptibil...

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Detalles Bibliográficos
Autores principales:	Wang, Xiao-Jian, Xu, Xi-Qi, Sun, Kai, Liu, Ke-Qiang, Li, Su-Qi, Jiang, Xin, Zhao, Qin-Hua, Wang, Lan, Peng, Fu-Hua, Ye, Jue, Wu, Yan, Jiang, Rui, Zhang, Jin, Huang, Wei, Wei, Wen-Bin, Yan, Yi, Li, Jing-Hui, Liu, Qian-Qian, Li, Sheng, Wang, Yong, Zhang, Shu-Yang, Zhang, Xue, Jing, Zhi-Cheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Medical Association 2020
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113838/ https://www.ncbi.nlm.nih.gov/pubmed/32236489 http://dx.doi.org/10.1001/jamacardio.2020.0479

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