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6-Thioguanine inhibits rotavirus replication through suppression of Rac1 GDP/GTP cycling
Rotavirus infection has emerged as an important cause of complications in organ transplantation recipients and might play a role in the pathogenesis of inflammatory bowel disease (IBD). 6-Thioguanine (6-TG) has been widely used as an immunosuppressive drug for organ recipients and treatment of IBD i...
Autores principales: | Yin, Yuebang, Chen, Sunrui, Hakim, Mohamad S., Wang, Wenshi, Xu, Lei, Dang, Wen, Qu, Changbo, Verhaar, Auke P., Su, Junhong, Fuhler, Gwenny M., Peppelenbosch, Maikel P., Pan, Qiuwei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Authors. Published by Elsevier B.V.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113846/ https://www.ncbi.nlm.nih.gov/pubmed/29920300 http://dx.doi.org/10.1016/j.antiviral.2018.06.011 |
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