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A monoclonal antibody binds to threonine 49 in the non-structural 1 protein of influenza A virus and interferes with its ability to modulate viral replication
The emergence of resistant influenza A viruses highlights the continuous requirement of new antiviral drugs that can treat the viral infection. Non-structural 1 (NS1) protein, an indispensable component for efficient virus replication, can be used as a potential target for generating new antiviral a...
Autores principales: | Barnwal, Bhaskar, Mok, Chee-Keng, Wu, Jianping, Diwakar, Mandakhalikar Kedar, Gupta, Garvita, Zeng, Qi, Chow, Vincent Tak Kwong, Song, Jianxing, Yuan, Y. Adam, Tan, Yee-Joo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113856/ https://www.ncbi.nlm.nih.gov/pubmed/25666762 http://dx.doi.org/10.1016/j.antiviral.2015.01.015 |
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