Rapid one-step construction of a Middle East Respiratory Syndrome (MERS-CoV) infectious clone system by homologous recombination

BACKGROUND: Viral Infectious clone systems serve as robust platforms to study viral gene or replicative function by reverse genetics, formulate vaccines and adapt a wild type-virus to an animal host. Since the development of the first viral infectious clone system for the poliovirus, novel strategie...

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Detalles Bibliográficos
Autores principales: Nikiforuk, Aidan M., Leung, Anders, Cook, Bradley W.M., Court, Deborah A., Kobasa, Darwyn, Theriault, Steven S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113859/
https://www.ncbi.nlm.nih.gov/pubmed/27459876
http://dx.doi.org/10.1016/j.jviromet.2016.07.022

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