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A recombinant VSV-vectored MERS-CoV vaccine induces neutralizing antibody and T cell responses in rhesus monkeys after single dose immunization

Middle East respiratory syndrome coronavirus (MERS-CoV) has been a highly threatening zoonotic pathogen since its outbreak in 2012. Similar to SARS-CoV, MERS-CoV belongs to the coronavirus family and can induce severe respiratory symptoms in humans, with an average case fatality rate of 35% accordin...

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Detalles Bibliográficos
Autores principales: Liu, Renqiang, Wang, Jinliang, Shao, Yu, Wang, Xijun, Zhang, Huilei, Shuai, Lei, Ge, Jinying, Wen, Zhiyuan, Bu, Zhigao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113862/
https://www.ncbi.nlm.nih.gov/pubmed/29246504
http://dx.doi.org/10.1016/j.antiviral.2017.12.007