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Rapid manipulation of the porcine epidemic diarrhea virus genome by CRISPR/Cas9 technology

Porcine epidemic diarrhea virus (PEDV) is a highly pathogenic enteric coronavirus causing lethal watery diarrhea in suckling piglets. Reverse genetics is a valuable tool to study the functions of viral genes and to generate vaccine candidates. In this study, a full-length infectious cDNA clone of th...

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Detalles Bibliográficos
Autores principales:	Peng, Qi, Fang, Liurong, Ding, Zhen, Wang, Dang, Peng, Guiqing, Xiao, Shaobo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier B.V. 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113866/ https://www.ncbi.nlm.nih.gov/pubmed/31712093 http://dx.doi.org/10.1016/j.jviromet.2019.113772

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