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Single dose of an adenovirus vectored mouse interferon-α protects mice from lethal EV71 challenge

Enterovirus 71 (EV71) causes hand-foot-and-mouth diseases as well as neurological complications in young children. Interferon (IFN) can inhibit the replication of many viruses with low cytotoxic effects. Previously, an adenovirus vectored mouse interferon-α (DEF201), subtype 5, was generated by Wu e...

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Detalles Bibliográficos
Autores principales:	Sun, Jialei, Ennis, Jane, Turner, Jeffrey D., Chu, Justin Jang Hann
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier B.V. 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113890/ https://www.ncbi.nlm.nih.gov/pubmed/27623347 http://dx.doi.org/10.1016/j.antiviral.2016.09.003

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