The Herpes Simplex Virus-1 genome contains multiple clusters of repeated G-quadruplex: Implications for the antiviral activity of a G-quadruplex ligand

Guanine-rich nucleic acids can fold into G-quadruplexes, secondary structures implicated in important regulatory functions at the genomic level in humans, prokaryotes and viruses. The remarkably high guanine content of the Herpes Simplex Virus-1 (HSV-1) genome prompted us to investigate both the pre...

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Detalles Bibliográficos
Autores principales: Artusi, Sara, Nadai, Matteo, Perrone, Rosalba, Biasolo, Maria Angela, Palù, Giorgio, Flamand, Louis, Calistri, Arianna, Richter, Sara N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113899/
https://www.ncbi.nlm.nih.gov/pubmed/25843424
http://dx.doi.org/10.1016/j.antiviral.2015.03.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113899/
https://www.ncbi.nlm.nih.gov/pubmed/25843424
http://dx.doi.org/10.1016/j.antiviral.2015.03.016

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