Efficient induction of cytotoxic T lymphocytes specific for severe acute respiratory syndrome (SARS)-associated coronavirus by immunization with surface-linked liposomal peptides derived from a non-structural polyprotein 1a

Spike and nucleocapsid are structural proteins of severe acute respiratory syndrome (SARS)-associated coronavirus (SARS-CoV) and major targets for cytotoxic T lymphocytes (CTLs). In contrast, non-structural proteins encoded by two-thirds of viral genome are poorly characterized for cell-mediated imm...

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Detalles Bibliográficos
Autores principales: Kohyama, Shunsuke, Ohno, Satoshi, Suda, Tatsuya, Taneichi, Maiko, Yokoyama, Shoichi, Mori, Masahito, Kobayashi, Akiharu, Hayashi, Hidenori, Uchida, Tetsuya, Matsui, Masanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114085/
https://www.ncbi.nlm.nih.gov/pubmed/19748524
http://dx.doi.org/10.1016/j.antiviral.2009.09.004

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