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Inhibitory effect of mizoribine and ribavirin on the replication of severe acute respiratory syndrome (SARS)-associated coronavirus
The activity of inosine-5′-monophosphate dehydrogenase (IMPDH) inhibitors, mizoribine and ribavirin, against severe acute respiratory syndrome (SARS)-associated coronavirus (SARS-CoV) was determined by plaque reduction and yield reduction assays. Mizoribine and ribavirin selectively inhibited replic...
Autores principales: | Saijo, Masayuki, Morikawa, Shigeru, Fukushi, Shuetsu, Mizutani, Tetsuya, Hasegawa, Hideki, Nagata, Noriyo, Iwata, Naoko, Kurane, Ichiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114120/ https://www.ncbi.nlm.nih.gov/pubmed/15911031 http://dx.doi.org/10.1016/j.antiviral.2005.01.003 |
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