Influences of cyclosporin A and non-immunosuppressive derivatives on cellular cyclophilins and viral nucleocapsid protein during human coronavirus 229E replication

The well-known immunosuppressive drug cyclosporin A inhibits replication of various viruses including coronaviruses by binding to cellular cyclophilins thus inactivating their cis-trans peptidyl-prolyl isomerase function. Viral nucleocapsid proteins are inevitable for genome encapsidation and replic...

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Detalles Bibliográficos
Autores principales: Ma-Lauer, Yue, Zheng, Yu, Malešević, Miroslav, von Brunn, Brigitte, Fischer, Gunter, von Brunn, Albrecht
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114175/
https://www.ncbi.nlm.nih.gov/pubmed/31634494
http://dx.doi.org/10.1016/j.antiviral.2019.104620

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114175/
https://www.ncbi.nlm.nih.gov/pubmed/31634494
http://dx.doi.org/10.1016/j.antiviral.2019.104620

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