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Rapid identification of inhibitors that interfere with poliovirus replication using a cell-based assay

A small molecule library containing 480 known bioactive compounds was screened for antiviral activity against poliovirus (PV) using a cellular fluorescence resonance energy transfer (FRET) assay for viral protease activity. The infected reporter cells treated with the viral replication-suppressing c...

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Detalles Bibliográficos
Autores principales:	Hwang, Yu-Chen, Chu, Justin Jang-Hann, Yang, Priscilla L., Chen, Wilfred, Yates, Marylynn V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier B.V. 2008
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114228/ https://www.ncbi.nlm.nih.gov/pubmed/18243348 http://dx.doi.org/10.1016/j.antiviral.2007.12.009

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