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Modifications in the branched arms of a class of dual inhibitors of HIV and EV71 replication expand their antiviral spectrum
We have previously reported a new class of dendrimers with tryptophan (Trp) residues on the surface that show dual antiviral activities against HIV and enterovirus EV71. The prototype compound of this family is a derivative of pentaerythritol with 12 peripheral Trp groups and trivalent spacer arms....
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114229/ https://www.ncbi.nlm.nih.gov/pubmed/31228490 http://dx.doi.org/10.1016/j.antiviral.2019.06.006 |