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Modifications in the branched arms of a class of dual inhibitors of HIV and EV71 replication expand their antiviral spectrum

We have previously reported a new class of dendrimers with tryptophan (Trp) residues on the surface that show dual antiviral activities against HIV and enterovirus EV71. The prototype compound of this family is a derivative of pentaerythritol with 12 peripheral Trp groups and trivalent spacer arms....

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Detalles Bibliográficos
Autores principales: Martínez-Gualda, Belén, Sun, Liang, Martí-Marí, Olaia, Mirabelli, Carmen, Delang, Leen, Neyts, Johan, Schols, Dominique, Camarasa, María-José, San-Félix, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114229/
https://www.ncbi.nlm.nih.gov/pubmed/31228490
http://dx.doi.org/10.1016/j.antiviral.2019.06.006

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