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Frequency of PRRS live vaccine virus (European and North American genotype) in vaccinated and non-vaccinated pigs submitted for respiratory tract diagnostics in North-Western Germany

The frequency of PRRSV corresponding to live vaccines and wild-type was determined in 902 pigs from North-Western Germany submitted for post-mortem examination. Overall, 18.5% of the samples were positive for the EU wild-type virus. EU genotype vaccine virus was detected in 1.3% and the NA genotype...

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Autores principales: grosse Beilage, Elisabeth, Nathues, Heiko, Meemken, Diana, Harder, Timm C., Doherr, Marcus G., Grotha, Inga, Greiser-Wilke, Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114236/
https://www.ncbi.nlm.nih.gov/pubmed/19700211
http://dx.doi.org/10.1016/j.prevetmed.2009.07.010
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author grosse Beilage, Elisabeth
Nathues, Heiko
Meemken, Diana
Harder, Timm C.
Doherr, Marcus G.
Grotha, Inga
Greiser-Wilke, Irene
author_facet grosse Beilage, Elisabeth
Nathues, Heiko
Meemken, Diana
Harder, Timm C.
Doherr, Marcus G.
Grotha, Inga
Greiser-Wilke, Irene
author_sort grosse Beilage, Elisabeth
collection PubMed
description The frequency of PRRSV corresponding to live vaccines and wild-type was determined in 902 pigs from North-Western Germany submitted for post-mortem examination. Overall, 18.5% of the samples were positive for the EU wild-type virus. EU genotype vaccine virus was detected in 1.3% and the NA genotype vaccine virus in 8.9% of all samples. The detection of the EU vaccine was significantly higher in pigs vaccinated with the corresponding vaccine (OR = 9.4). Pigs vaccinated with NA genotype had significantly higher detection chances for the corresponding vaccine virus when compared to non-vaccinated animals (OR = 3.34) animals, however, NA vaccine was also frequently detected in non-vaccinated pigs. Concluding, the dynamics of NA genotype vaccine and EU wild-type virus corresponds with studies on PRRSV spread in endemically infected herds. The potential of spontaneous spread of the NA genotype vaccine should be considered in the planning of eradication programs.
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spelling pubmed-71142362020-04-02 Frequency of PRRS live vaccine virus (European and North American genotype) in vaccinated and non-vaccinated pigs submitted for respiratory tract diagnostics in North-Western Germany grosse Beilage, Elisabeth Nathues, Heiko Meemken, Diana Harder, Timm C. Doherr, Marcus G. Grotha, Inga Greiser-Wilke, Irene Prev Vet Med Article The frequency of PRRSV corresponding to live vaccines and wild-type was determined in 902 pigs from North-Western Germany submitted for post-mortem examination. Overall, 18.5% of the samples were positive for the EU wild-type virus. EU genotype vaccine virus was detected in 1.3% and the NA genotype vaccine virus in 8.9% of all samples. The detection of the EU vaccine was significantly higher in pigs vaccinated with the corresponding vaccine (OR = 9.4). Pigs vaccinated with NA genotype had significantly higher detection chances for the corresponding vaccine virus when compared to non-vaccinated animals (OR = 3.34) animals, however, NA vaccine was also frequently detected in non-vaccinated pigs. Concluding, the dynamics of NA genotype vaccine and EU wild-type virus corresponds with studies on PRRSV spread in endemically infected herds. The potential of spontaneous spread of the NA genotype vaccine should be considered in the planning of eradication programs. Elsevier B.V. 2009-11-01 2009-08-22 /pmc/articles/PMC7114236/ /pubmed/19700211 http://dx.doi.org/10.1016/j.prevetmed.2009.07.010 Text en Copyright © 2009 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
grosse Beilage, Elisabeth
Nathues, Heiko
Meemken, Diana
Harder, Timm C.
Doherr, Marcus G.
Grotha, Inga
Greiser-Wilke, Irene
Frequency of PRRS live vaccine virus (European and North American genotype) in vaccinated and non-vaccinated pigs submitted for respiratory tract diagnostics in North-Western Germany
title Frequency of PRRS live vaccine virus (European and North American genotype) in vaccinated and non-vaccinated pigs submitted for respiratory tract diagnostics in North-Western Germany
title_full Frequency of PRRS live vaccine virus (European and North American genotype) in vaccinated and non-vaccinated pigs submitted for respiratory tract diagnostics in North-Western Germany
title_fullStr Frequency of PRRS live vaccine virus (European and North American genotype) in vaccinated and non-vaccinated pigs submitted for respiratory tract diagnostics in North-Western Germany
title_full_unstemmed Frequency of PRRS live vaccine virus (European and North American genotype) in vaccinated and non-vaccinated pigs submitted for respiratory tract diagnostics in North-Western Germany
title_short Frequency of PRRS live vaccine virus (European and North American genotype) in vaccinated and non-vaccinated pigs submitted for respiratory tract diagnostics in North-Western Germany
title_sort frequency of prrs live vaccine virus (european and north american genotype) in vaccinated and non-vaccinated pigs submitted for respiratory tract diagnostics in north-western germany
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114236/
https://www.ncbi.nlm.nih.gov/pubmed/19700211
http://dx.doi.org/10.1016/j.prevetmed.2009.07.010
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