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A novel recombinant bacterial vaccine strain expressing dual viral antigens induces multiple immune responses to the Gag and gp120 proteins of HIV-1 in immunized mice

Recombinant Salmonella enterica serovar Typhi can function as a live vector to deliver foreign antigens to the mammalian immune system and induce both mucosal and systemic immunity. In this study, we generated a recombinant Salmonella Typhi strain pilS(−)pilT(−)Gag(+)(pVAX1-gp120) harboring the huma...

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Detalles Bibliográficos
Autores principales:	Feng, Yong, Wang, Shiqun, Luo, Fenglin, Ruan, Ying, Kang, Lei, Xiang, Xiaohui, Chao, Tao, Peng, Guiqing, Zhu, Chengliang, Mu, Yongxin, Zhu, Ying, Zhang, Xiaolian, Wu, Jianguo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier B.V. 2008
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114238/ https://www.ncbi.nlm.nih.gov/pubmed/18639586 http://dx.doi.org/10.1016/j.antiviral.2008.06.013

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