TACE antagonists blocking ACE2 shedding caused by the spike protein of SARS-CoV are candidate antiviral compounds

Because outbreaks of severe acute respiratory syndrome coronavirus (SARS-CoV) might reemerge, identifying antiviral compounds is of key importance. Previously, we showed that the cellular factor TNF-α converting enzyme (TACE), activated by the spike protein of SARS-CoV (SARS-S protein), was positive...

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Detalles Bibliográficos
Autores principales: Haga, Shiori, Nagata, Noriyo, Okamura, Tadashi, Yamamoto, Norio, Sata, Tetsutaro, Yamamoto, Naoki, Sasazuki, Takehiko, Ishizaka, Yukihito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2010
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114272/
https://www.ncbi.nlm.nih.gov/pubmed/19995578
http://dx.doi.org/10.1016/j.antiviral.2009.12.001

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