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Structure-based antigen design: a strategy for next generation vaccines

Vaccine design is progressing from empiricism towards the increasingly rational presentation of the targets of protective immunity. Nevertheless, most current vaccine antigens are essentially the native macromolecules of pathogens. These molecules are adapted to evade, not induce, immunity. High res...

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Detalles Bibliográficos
Autores principales: Dormitzer, Philip R., Ulmer, Jeffrey B., Rappuoli, Rino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114313/
https://www.ncbi.nlm.nih.gov/pubmed/18977045
http://dx.doi.org/10.1016/j.tibtech.2008.08.002