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Anti-SARS coronavirus 3C-like protease effects of Isatis indigotica root and plant-derived phenolic compounds

The 3C-like protease (3CL(pro)) of SARS-coronavirus mediates the proteolytic processing of replicase polypeptides 1a and 1ab into functional proteins, becoming an important target for the drug development. In this study, Isatis indigotica root extract, five major compounds of I. indigotica root, and...

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Detalles Bibliográficos
Autores principales:	Lin, Cheng-Wen, Tsai, Fuu-Jen, Tsai, Chang-Hai, Lai, Chien-Chen, Wan, Lei, Ho, Tin-Yun, Hsieh, Chang-Chi, Chao, Pei-Dawn Lee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier B.V. 2005
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114321/ https://www.ncbi.nlm.nih.gov/pubmed/16115693 http://dx.doi.org/10.1016/j.antiviral.2005.07.002

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