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Up-regulation of IL-6 and TNF-α induced by SARS-coronavirus spike protein in murine macrophages via NF-κB pathway

The clinical picture of severe acute respiratory syndrome (SARS) is characterized by an over-exuberant immune response with lung lymphomononuclear cells infilteration and proliferation that may account for tissue damage more than the direct effect of viral replication. To understand how cells respon...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Ye, Linbai, Ye, Li, Li, Baozong, Gao, Bo, Zeng, Yingchun, Kong, Lingbao, Fang, Xiaonan, Zheng, Hong, Wu, Zhenghui, She, Yinglong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114322/
https://www.ncbi.nlm.nih.gov/pubmed/17532082
http://dx.doi.org/10.1016/j.virusres.2007.02.007