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Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 interaction

Severe acute respiratory syndrome (SARS) is an emerging infectious disease caused by a novel coronavirus (SARS-CoV). SARS-CoV spike (S) protein, a type I membrane-bound protein, is essential for the viral attachment to the host cell receptor angiotensin-converting enzyme 2 (ACE2). By screening 312 c...

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Detalles Bibliográficos
Autores principales: Ho, Tin-Yun, Wu, Shih-Lu, Chen, Jaw-Chyun, Li, Chia-Cheng, Hsiang, Chien-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114332/
https://www.ncbi.nlm.nih.gov/pubmed/16730806
http://dx.doi.org/10.1016/j.antiviral.2006.04.014

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