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Molecular modeling and analysis of hepatitis E virus (HEV) papain-like cysteine protease

The biochemical or biophysical characterization of a papain-like cysteine protease in HEV ORF1-encoded polyprotein still remains elusive. Very recently, we have demonstrated the indispensability of ORF1 protease-domain cysteines and histidines in HEV replication, ex vivo (Parvez, 2013). In this repo...

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Detalles Bibliográficos
Autores principales: Parvez, Mohammad Khalid, Khan, Azmat Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114377/
https://www.ncbi.nlm.nih.gov/pubmed/24321124
http://dx.doi.org/10.1016/j.virusres.2013.11.016