Molecular characterization of a virulent canine coronavirus BGF strain()

Molecular characterisation of a canine coronavirus (CCoV) isolate (BGF), associated with an outbreak of diarrhoea in puppies, showed 92.7% identity with attenuated Insavc-1 strain. Canine coronavirus BGF revealed a full length non-structural protein 3b (nsp 3b), associated with virulence in other co...

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Detalles Bibliográficos
Autores principales: Sanchez-Morgado, Jose M, Poynter, Scott, Morris, Timothy H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2004
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114380/
https://www.ncbi.nlm.nih.gov/pubmed/15177889
http://dx.doi.org/10.1016/j.virusres.2004.02.038
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author Sanchez-Morgado, Jose M
Poynter, Scott
Morris, Timothy H
author_facet Sanchez-Morgado, Jose M
Poynter, Scott
Morris, Timothy H
author_sort Sanchez-Morgado, Jose M
collection PubMed
description Molecular characterisation of a canine coronavirus (CCoV) isolate (BGF), associated with an outbreak of diarrhoea in puppies, showed 92.7% identity with attenuated Insavc-1 strain. Canine coronavirus BGF revealed a full length non-structural protein 3b (nsp 3b), associated with virulence in other coronaviruses, and a highly divergent region at the amino terminal domain of the membrane protein that may be implicated in avoiding the host immune reaction. This new canine coronavirus strain could help to identify virulence factors in coronavirus.
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spelling pubmed-71143802020-04-02 Molecular characterization of a virulent canine coronavirus BGF strain() Sanchez-Morgado, Jose M Poynter, Scott Morris, Timothy H Virus Res Article Molecular characterisation of a canine coronavirus (CCoV) isolate (BGF), associated with an outbreak of diarrhoea in puppies, showed 92.7% identity with attenuated Insavc-1 strain. Canine coronavirus BGF revealed a full length non-structural protein 3b (nsp 3b), associated with virulence in other coronaviruses, and a highly divergent region at the amino terminal domain of the membrane protein that may be implicated in avoiding the host immune reaction. This new canine coronavirus strain could help to identify virulence factors in coronavirus. Elsevier B.V. 2004-08 2004-04-22 /pmc/articles/PMC7114380/ /pubmed/15177889 http://dx.doi.org/10.1016/j.virusres.2004.02.038 Text en Copyright © 2004 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Sanchez-Morgado, Jose M
Poynter, Scott
Morris, Timothy H
Molecular characterization of a virulent canine coronavirus BGF strain()
title Molecular characterization of a virulent canine coronavirus BGF strain()
title_full Molecular characterization of a virulent canine coronavirus BGF strain()
title_fullStr Molecular characterization of a virulent canine coronavirus BGF strain()
title_full_unstemmed Molecular characterization of a virulent canine coronavirus BGF strain()
title_short Molecular characterization of a virulent canine coronavirus BGF strain()
title_sort molecular characterization of a virulent canine coronavirus bgf strain()
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114380/
https://www.ncbi.nlm.nih.gov/pubmed/15177889
http://dx.doi.org/10.1016/j.virusres.2004.02.038
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