Cellular, transcriptomic and isoform heterogeneity of breast cancer cell line revealed by full-length single-cell RNA sequencing

Tumor heterogeneity is generated through a combination of genetic and epigenetic mechanisms, the latter of which plays an important role in the generation of stem like cells responsible for tumor formation and metastasis. Although the development of single cell transcriptomic technologies holds prom...

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Detalles Bibliográficos
Autores principales: Wu, Shaocheng, Zhang, Hongjiu, Fouladdel, Shamileh, Li, Hongyang, Keller, Evan, Wicha, Max S., Omenn, Gilbert S., Azizi, Ebrahim, Guan, Yuanfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114460/
https://www.ncbi.nlm.nih.gov/pubmed/32257051
http://dx.doi.org/10.1016/j.csbj.2020.03.005

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