Effects of hypervariable regions in spike protein on pathogenicity, tropism, and serotypes of infectious bronchitis virus

To study the roles of hypervariable regions (HVRs) in receptor-binding subunit S1 of the spike protein, we manipulated the genome of the IBV Beaudette strain using a reverse genetics system to construct seven recombinant strains by separately or simultaneously replacing the three HVRs of the Beaudet...

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Detalles Bibliográficos
Autores principales: Shan, Dan, Fang, Shouguo, Han, Zongxi, Ai, Hui, Zhao, Wenjun, Chen, Yuqiu, Jiang, Lei, Liu, Shengwang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114591/
https://www.ncbi.nlm.nih.gov/pubmed/29684409
http://dx.doi.org/10.1016/j.virusres.2018.04.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114591/
https://www.ncbi.nlm.nih.gov/pubmed/29684409
http://dx.doi.org/10.1016/j.virusres.2018.04.013

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