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Experimental Treatment of SIV-Infected Macaques via Autograft of CCR5-Disrupted Hematopoietic Stem and Progenitor Cells

Hematopoietic stem cell (HSC)-based gene therapy targeting CCR5 represents a promising way to cure human immunodeficiency virus type 1 (HIV-1) infection. Yet the preclinical animal model with transplantation of autologous CCR5-ablated HSCs remains to be optimized. In this study, four Chinese rhesus...

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Detalles Bibliográficos
Autores principales:	Yu, Songlin, Ou, Yang, Xiao, Hongkui, Li, Jiaojiao, Adah, Dickson, Liu, Shiquan, Zhao, Siting, Qin, Li, Yao, Yongchao, Chen, Xiaoping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114624/ https://www.ncbi.nlm.nih.gov/pubmed/32258215 http://dx.doi.org/10.1016/j.omtm.2020.03.004

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