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Giving the Genes a Shuffle: Using Natural Variation to Understand Host Genetic Contributions to Viral Infections
The laboratory mouse has proved an invaluable model to identify host factors that regulate the progression and outcome of virus-induced disease. The paradigm is to use single-gene knockouts in inbred mouse strains or genetic mapping studies using biparental mouse populations. However, genetic variat...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier Ltd.
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114642/ https://www.ncbi.nlm.nih.gov/pubmed/30131185 http://dx.doi.org/10.1016/j.tig.2018.07.005 |