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Primary melanoma of the cornea
Purpose: To present an extremely rare case of corneal melanoma. Method: An 84-year-old female patient presented to our department with a pigmented corneal lesion in her right eye (OD), 6x4 mm, complaining of mild pain and inability of complete eyelid closure. Tumor growth had been noted the previous...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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German Medical Science GMS Publishing House
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114650/ https://www.ncbi.nlm.nih.gov/pubmed/32269910 http://dx.doi.org/10.3205/oc000139 |
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author | Panagiotou, Dimitrios Z. Chranioti, Angeliki A. Tzorakoleftheraki, Sofia-Eleni Ziakas, Nikolaos G. Oikonomidis, Panagiotis K. |
author_facet | Panagiotou, Dimitrios Z. Chranioti, Angeliki A. Tzorakoleftheraki, Sofia-Eleni Ziakas, Nikolaos G. Oikonomidis, Panagiotis K. |
author_sort | Panagiotou, Dimitrios Z. |
collection | PubMed |
description | Purpose: To present an extremely rare case of corneal melanoma. Method: An 84-year-old female patient presented to our department with a pigmented corneal lesion in her right eye (OD), 6x4 mm, complaining of mild pain and inability of complete eyelid closure. Tumor growth had been noted the previous year. She had undergone cataract surgery in her right eye three years before, followed by an unspecified postoperative complication. Her visual acuity was 3/10 OD and 9/10 OS. Ophthalmic evaluation and ultrasonography (A- and B-scan) did not reveal any other pathology. The pigmented lesion was surgically removed and the patient underwent a protocol therapy of topical chemotherapy (mitomycin 0.03%, 2x4 for 2 weeks and dexamethasone 0.1%, 2x4 for the following 2 weeks, followed by another cycle of mitomycin 0.03%, 2x4 for another 2 weeks). Results: The surgical removal of the lesion was uncomplicated, as was the postoperative period. The patient’s visual acuity improved to 6/10 three months postoperatively. The histologic examination revealed malignant melanoma. Conclusions: Despite its rarity, primary melanoma of the cornea is an existing entity. Treatment of corneal melanoma consists of surgical removal and postoperative topical chemotherapy. Postoperative follow-up is mandatory. |
format | Online Article Text |
id | pubmed-7114650 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | German Medical Science GMS Publishing House |
record_format | MEDLINE/PubMed |
spelling | pubmed-71146502020-04-08 Primary melanoma of the cornea Panagiotou, Dimitrios Z. Chranioti, Angeliki A. Tzorakoleftheraki, Sofia-Eleni Ziakas, Nikolaos G. Oikonomidis, Panagiotis K. GMS Ophthalmol Cases Article Purpose: To present an extremely rare case of corneal melanoma. Method: An 84-year-old female patient presented to our department with a pigmented corneal lesion in her right eye (OD), 6x4 mm, complaining of mild pain and inability of complete eyelid closure. Tumor growth had been noted the previous year. She had undergone cataract surgery in her right eye three years before, followed by an unspecified postoperative complication. Her visual acuity was 3/10 OD and 9/10 OS. Ophthalmic evaluation and ultrasonography (A- and B-scan) did not reveal any other pathology. The pigmented lesion was surgically removed and the patient underwent a protocol therapy of topical chemotherapy (mitomycin 0.03%, 2x4 for 2 weeks and dexamethasone 0.1%, 2x4 for the following 2 weeks, followed by another cycle of mitomycin 0.03%, 2x4 for another 2 weeks). Results: The surgical removal of the lesion was uncomplicated, as was the postoperative period. The patient’s visual acuity improved to 6/10 three months postoperatively. The histologic examination revealed malignant melanoma. Conclusions: Despite its rarity, primary melanoma of the cornea is an existing entity. Treatment of corneal melanoma consists of surgical removal and postoperative topical chemotherapy. Postoperative follow-up is mandatory. German Medical Science GMS Publishing House 2020-03-18 /pmc/articles/PMC7114650/ /pubmed/32269910 http://dx.doi.org/10.3205/oc000139 Text en Copyright © 2020 Panagiotou et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License. See license information at http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Panagiotou, Dimitrios Z. Chranioti, Angeliki A. Tzorakoleftheraki, Sofia-Eleni Ziakas, Nikolaos G. Oikonomidis, Panagiotis K. Primary melanoma of the cornea |
title | Primary melanoma of the cornea |
title_full | Primary melanoma of the cornea |
title_fullStr | Primary melanoma of the cornea |
title_full_unstemmed | Primary melanoma of the cornea |
title_short | Primary melanoma of the cornea |
title_sort | primary melanoma of the cornea |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114650/ https://www.ncbi.nlm.nih.gov/pubmed/32269910 http://dx.doi.org/10.3205/oc000139 |
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