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Decreased NHE3 activity and trafficking in TGEV-infected IPEC-J2 cells via the SGLT1-mediated P38 MAPK/AKt2 pathway

Transmissible gastroenteritis virus (TGEV) primarily replicates in intestinal epithelial cells and causes severe damage to host cells, resulting in diarrhea. Surface NHE3 serves as the key regulatory site controlling electroneutral Na(+) absorption. In this study, our results showed that the surface...

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Detalles Bibliográficos
Autores principales: Yang, Yang, Yu, Qiuhan, Song, Han, Ran, Ling, Wang, Kai, Xie, Luyi, Huang, Shilei, Niu, Zheng, Zhang, Yilin, Kan, Zifei, Yan, Tao, Song, Zhenhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114662/
https://www.ncbi.nlm.nih.gov/pubmed/32070687
http://dx.doi.org/10.1016/j.virusres.2020.197901

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