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Homology Modeling of Human Uridine-5′-diphosphate-glucuronosyltransferase 1A6 Reveals Insights into Factors Influencing Substrate and Cosubstrate Binding

[Image: see text] The elimination of numerous endogenous compounds and xenobiotics via glucuronidation by uridine-5′-diphosphate glycosyltransferase enzymes (UGTs) is an essential process of the body’s chemical defense system. UGTs have distinct but overlapping substrate preferences, but the molecul...

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Detalles Bibliográficos
Autores principales:	Smith, Alexander D., Page, Brent D. G., Collier, Abby C., Coughtrie, Michael W. H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2020
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114752/ https://www.ncbi.nlm.nih.gov/pubmed/32258923 http://dx.doi.org/10.1021/acsomega.0c00205

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