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Quantum Chemical Lipophilicities of Antimalarial Drugs in Relation to Terminal Half-Life
[Image: see text] According to the WHO, artemisinin-based combination therapies (ACTs) have been integral to the recent reduction in deaths due to Plasmodium falciparum malaria. ACT-resistant strains are an emerging problem and have evolved altered developmental stages, reducing exposure of the most...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114756/ https://www.ncbi.nlm.nih.gov/pubmed/32258886 http://dx.doi.org/10.1021/acsomega.9b04140 |