Substituted imidazopyridines as potent inhibitors of HCV replication()

BACKGROUND/AIMS: Following lead optimization, a set of substituted imidazopyridines was identified as potent and selective inhibitors of in vitro HCV replication. The particular characteristics of one of the most potent compounds in this series (5-[[3-(4-chlorophenyl)-5-isoxazolyl]methyl]-2-(2,3-dif...

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Detalles Bibliográficos
Autores principales: Vliegen, Inge, Paeshuyse, Jan, De Burghgraeve, Tine, Lehman, Laura S., Paulson, Matthew, Shih, I-Hung, Mabery, Eric, Boddeker, Nina, De Clercq, Erik, Reiser, Hans, Oare, David, Lee, William A., Zhong, Weidong, Bondy, Steven, Pürstinger, Gerhard, Neyts, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Association for the Study of the Liver. Published by Elsevier Ireland Ltd. 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114863/
https://www.ncbi.nlm.nih.gov/pubmed/19303654
http://dx.doi.org/10.1016/j.jhep.2008.12.028

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