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Transcriptomic profiling of microglia and astrocytes throughout aging
BACKGROUND: Activation of microglia and astrocytes, a prominent hallmark of both aging and Alzheimer’s disease (AD), has been suggested to contribute to aging and AD progression, but the underlying cellular and molecular mechanisms are largely unknown. METHODS: We performed RNA-seq analyses on micro...
Autores principales: | Pan, Jie, Ma, Nana, Yu, Bo, Zhang, Wei, Wan, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115095/ https://www.ncbi.nlm.nih.gov/pubmed/32238175 http://dx.doi.org/10.1186/s12974-020-01774-9 |
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