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Ubiquitin Linkage Specificity of Deubiquitinases Determines Cyclophilin Nuclear Localization and Degradation
Ubiquitin chain specificity has been described for some deubiquitinases (DUBs) but lacks a comprehensive profiling in vivo. We used quantitative proteomics to compare the seven lysine-linked ubiquitin chains between wild-type yeast and its 20 DUB-deletion strains, which may reflect the linkage speci...
Autores principales: | Li, Yanchang, Lan, Qiuyan, Gao, Yuan, Xu, Cong, Xu, Zhongwei, Wang, Yihao, Chang, Lei, Wu, Junzhu, Deng, Zixin, He, Fuchu, Finley, Daniel, Xu, Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115106/ https://www.ncbi.nlm.nih.gov/pubmed/32240951 http://dx.doi.org/10.1016/j.isci.2020.100984 |
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