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Mitochondria at the crossroads of ATM-mediated stress signaling and regulation of reactive oxygen species

The Ataxia-telangiectasia mutated (ATM) kinase responds to DNA double-strand breaks and other forms of cellular stress, including reactive oxygen species (ROS). Recent work in the field has uncovered links between mitochondrial ROS and ATM activation, suggesting that ATM acts as a sensor for mitocho...

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Detalles Bibliográficos
Autores principales:	Lee, Ji-Hoon, Paull, Tanya T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Mini Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115119/ https://www.ncbi.nlm.nih.gov/pubmed/32244177 http://dx.doi.org/10.1016/j.redox.2020.101511

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