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Noncanonical Roles of hα-syn (A53T) in the Pathogenesis of Parkinson's Disease: Synaptic Pathology and Neuronal Aging

The motor and nonmotor symptoms of PD involve several brain regions. However, whether α-syn pathology originating from the SNc can directly lead to the pathological changes in distant cerebral regions and induce PD-related symptoms remains unclear. Here, AAV9-synapsin-mCherry-human SNCA (A53T) was i...

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Detalles Bibliográficos
Autores principales:	Wang, Qing-Jun, Chen, An-Di, Chen, Hai-Chao, Wang, Dong-Xin, Cai, Yi-Ting, Yin, Jie, Jing, Yu-Hong, Gao, Li-Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115172/ https://www.ncbi.nlm.nih.gov/pubmed/32273890 http://dx.doi.org/10.1155/2020/6283754

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