Fatal multiorgan failure due to yellow fever vaccine-associated viscerotropic disease

Yellow fever vaccine-associated viscerotropic disease (YEL-AVD) is a rare complication of yellow fever (YF) vaccination. A previously healthy 22-year-old female died following YF vaccination despite aggressive measures. Serial viral load titers, cytokine levels and host genetic factors were evaluate...

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Autores principales: Belsher, Jon L., Gay, Peter, Brinton, Margo, DellaValla, Joseph, Ridenour, Robert, Lanciotti, Robert, Perelygin, Andrey, Zaki, Sherif, Paddock, Christopher, Querec, Troy, Zhu, Tuofu, Pulendran, Bali, Eidex, Rachel B., Hayes, Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2007
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115366/
https://www.ncbi.nlm.nih.gov/pubmed/18023511
http://dx.doi.org/10.1016/j.vaccine.2007.08.061
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author Belsher, Jon L.
Gay, Peter
Brinton, Margo
DellaValla, Joseph
Ridenour, Robert
Lanciotti, Robert
Perelygin, Andrey
Zaki, Sherif
Paddock, Christopher
Querec, Troy
Zhu, Tuofu
Pulendran, Bali
Eidex, Rachel B.
Hayes, Edward
author_facet Belsher, Jon L.
Gay, Peter
Brinton, Margo
DellaValla, Joseph
Ridenour, Robert
Lanciotti, Robert
Perelygin, Andrey
Zaki, Sherif
Paddock, Christopher
Querec, Troy
Zhu, Tuofu
Pulendran, Bali
Eidex, Rachel B.
Hayes, Edward
author_sort Belsher, Jon L.
collection PubMed
description Yellow fever vaccine-associated viscerotropic disease (YEL-AVD) is a rare complication of yellow fever (YF) vaccination. A previously healthy 22-year-old female died following YF vaccination despite aggressive measures. Serial viral load titers, cytokine levels and host genetic factors were evaluated in an attempt to understand this unusual and lethal outcome. The patient's high-titer vaccine viremia and possibly related minor genetic anomalies provide clues to exploring the etiology of YEL-AVD.
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spelling pubmed-71153662020-04-02 Fatal multiorgan failure due to yellow fever vaccine-associated viscerotropic disease Belsher, Jon L. Gay, Peter Brinton, Margo DellaValla, Joseph Ridenour, Robert Lanciotti, Robert Perelygin, Andrey Zaki, Sherif Paddock, Christopher Querec, Troy Zhu, Tuofu Pulendran, Bali Eidex, Rachel B. Hayes, Edward Vaccine Article Yellow fever vaccine-associated viscerotropic disease (YEL-AVD) is a rare complication of yellow fever (YF) vaccination. A previously healthy 22-year-old female died following YF vaccination despite aggressive measures. Serial viral load titers, cytokine levels and host genetic factors were evaluated in an attempt to understand this unusual and lethal outcome. The patient's high-titer vaccine viremia and possibly related minor genetic anomalies provide clues to exploring the etiology of YEL-AVD. Elsevier Ltd. 2007-12-05 2007-09-18 /pmc/articles/PMC7115366/ /pubmed/18023511 http://dx.doi.org/10.1016/j.vaccine.2007.08.061 Text en Copyright © 2007 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Belsher, Jon L.
Gay, Peter
Brinton, Margo
DellaValla, Joseph
Ridenour, Robert
Lanciotti, Robert
Perelygin, Andrey
Zaki, Sherif
Paddock, Christopher
Querec, Troy
Zhu, Tuofu
Pulendran, Bali
Eidex, Rachel B.
Hayes, Edward
Fatal multiorgan failure due to yellow fever vaccine-associated viscerotropic disease
title Fatal multiorgan failure due to yellow fever vaccine-associated viscerotropic disease
title_full Fatal multiorgan failure due to yellow fever vaccine-associated viscerotropic disease
title_fullStr Fatal multiorgan failure due to yellow fever vaccine-associated viscerotropic disease
title_full_unstemmed Fatal multiorgan failure due to yellow fever vaccine-associated viscerotropic disease
title_short Fatal multiorgan failure due to yellow fever vaccine-associated viscerotropic disease
title_sort fatal multiorgan failure due to yellow fever vaccine-associated viscerotropic disease
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115366/
https://www.ncbi.nlm.nih.gov/pubmed/18023511
http://dx.doi.org/10.1016/j.vaccine.2007.08.061
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