Immunogenicity, safety, and protective efficacy of an inactivated SARS-associated coronavirus vaccine in rhesus monkeys

An inactivated vaccine for severe acute respiratory syndrome (SARS)-associated coronavirus (SARS-CoV) was evaluated in rhesus monkeys. The monkeys were inoculated intramuscularly (i.m.) with 0.5, 5, 50, or 5000 μg of vaccine, or PBS as control, and boosted on day 7. After 3 weeks, they were challeng...

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Detalles Bibliográficos
Autores principales: Zhou, Jun, Wang, Wei, Zhong, Qiong, Hou, Wei, Yang, Zhanqiu, Xiao, Shu-Yuan, Zhu, Runqing, Tang, Zhijiao, Wang, Yong, Xian, Qiaoyang, Tang, Hongbing, Wen, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115379/
https://www.ncbi.nlm.nih.gov/pubmed/15837221
http://dx.doi.org/10.1016/j.vaccine.2004.11.075

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